{"created":"2023-05-15T13:57:25.654049+00:00","id":120,"links":{},"metadata":{"_buckets":{"deposit":"4d947801-2749-4ebc-84cc-90f02c9c0337"},"_deposit":{"created_by":16,"id":"120","owners":[16],"pid":{"revision_id":0,"type":"depid","value":"120"},"status":"published"},"_oai":{"id":"oai:osaka-dent.repo.nii.ac.jp:00000120","sets":["1686642104765:1:12:13"]},"author_link":["462","463"],"item_10006_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"マウス頭蓋冠臨界骨欠損モデルを用いた粒径の異なるα型第三リン酸カルシウム顆粒の骨形成能の比較"}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2016-03-11"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"大阪歯科大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"34408","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（歯学）"}]},"item_10006_description_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2015","subitem_description_type":"Other"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Alpha-tricalcium phosphate (α-TCP) has been investigated extensively as an artificial bone graft; however, the relationship between size of α-TCP particles and its bone-formation capability is not clear. In the present study, we compared the bone-formation capability of two different sized porous α-TCP particles (α-TCP200 [under 200 μm], and α-TCP600 [500–600 μm]) in critical-sized bone defects in mouse calvaria up to 12 wk after implantation. Scanning electron microscopy revealed that both particles possessed similar smooth surface with porous structure. Before implantation, inter-particle size and specific surface area of α-TCP200 were 27 μm and 0.40 m2/g and of α-TCP600 were 209 μm and 0.24m2/g, respectively. Histomorphometric analysis after implantation of the particles revealed that both particles promoted osteoconduction. At 12 wk, α-TCP200 induced superior bone formation than α-TCP600. At 4 wk, α-TCP200 showed more hydrolysis than α-TCP600. These results indicate that the size of α-TCP particles may influence their bone-formation capability in critical-sized bone defects of mouse calvaria. This effect might be partially due to the difference in the hydrolysis speed of different-sized particles.","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第784号"}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"徳田, 知子"},{"creatorName":"トクダ, トモコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tokuda, Tomoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-08-01"}],"displaytype":"detail","filename":"kou_784_txt.pdf","filesize":[{"value":"675.8 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"学位論文","url":"https://osaka-dent.repo.nii.ac.jp/record/120/files/kou_784_txt.pdf"},"version_id":"586114d3-f0bb-45db-aeaf-6929d67dd0f9"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-08-01"}],"displaytype":"detail","filename":"kou_784.pdf","filesize":[{"value":"229.1 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"論文内容要旨・審査結果要旨","url":"https://osaka-dent.repo.nii.ac.jp/record/120/files/kou_784.pdf"},"version_id":"8c381b1b-bcfd-4149-90e6-096595a4f317"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"alpha tricalcium phosphate","subitem_subject_scheme":"Other"},{"subitem_subject":"bone formation","subitem_subject_scheme":"Other"},{"subitem_subject":"particle","subitem_subject_scheme":"Other"},{"subitem_subject":"calvaria","subitem_subject_scheme":"Other"},{"subitem_subject":"hydrolysis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Comparison of the bone forming ability of different sized-alpha tricalcium phosphate granules using a critical size defect model of the mouse calvaria","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comparison of the bone forming ability of different sized-alpha tricalcium phosphate granules using a critical size defect model of the mouse calvaria"}]},"item_type_id":"10006","owner":"16","path":["13"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-08-01"},"publish_date":"2016-08-01","publish_status":"0","recid":"120","relation_version_is_last":true,"title":["Comparison of the bone forming ability of different sized-alpha tricalcium phosphate granules using a critical size defect model of the mouse calvaria"],"weko_creator_id":"16","weko_shared_id":-1},"updated":"2023-05-15T14:13:33.114128+00:00"}