{"created":"2023-05-15T13:57:27.268321+00:00","id":157,"links":{},"metadata":{"_buckets":{"deposit":"88dc6528-07cc-49f5-903f-6a105403b9a4"},"_deposit":{"created_by":16,"id":"157","owners":[16],"pid":{"revision_id":0,"type":"depid","value":"157"},"status":"published"},"_oai":{"id":"oai:osaka-dent.repo.nii.ac.jp:00000157","sets":["1686642104765:1:16:17"]},"author_link":["528"],"item_10006_alternative_title_1":{"attribute_name":"その他(別言語等)のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"γ-ポリグルタミン酸配合保湿スプレーの口腔内環境の変化についての検討"}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2017-03-10"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"大阪歯科大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"34408","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(歯学)"}]},"item_10006_description_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2016年度","subitem_description_type":"Other"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: This study was to evaluate the effect of new spray-type oral moisturizer containing poly-γ-glutamic acid (γ-PGA). γ-PGA can be classified as a pseudopolyamino acid, which contains only repeated glutamate units. The hygroscopic and moisturizing effects of γ-PGA were compared with HA. Cross-linked γ-PGA could absorb thousands of times more water than its own weight.\nMethods: 102 volunteers were randomly allocated to experimental and control groups. The experimental group (50 subjects) used this new moisturizer, the control group I (20 subjects) used sterile distilled water at normal temperature, and the control group II (32 subjects) used nothing. In experimental group, the effect of moisturizer was investigated by measuring amylase activity (salivary amylase monitor®), oral moisture (Mucus®), stimulated salivary flow rates at predetermine times (Saxon test).\nResults: In the amylase activity and the oral moisture, there was not a significant difference in all groups. In the stimulated salivary flow rates, there was a significant difference. When we compared the experimental group with the control group I, an increase was admitted at after 30 min (p < 0.05). When we compared the experimental group with the control group II, an increase was admitted at after 10 (p < 0.01), 20 (p < 0.05), 30 min (p < 0.05).\nConclusions: New moisturizer was able to improve the environment in the mouth. Oral application of γ-PGA has a possibility to be a therapeutic strategy for treating Xerostomia.","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第799号"}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山本, 翔一"},{"creatorName":"ヤマモト, ショウイチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"528","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-09-08"}],"displaytype":"detail","filename":"kou_799_txt.pdf","filesize":[{"value":"211.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"学位論文","url":"https://osaka-dent.repo.nii.ac.jp/record/157/files/kou_799_txt.pdf"},"version_id":"90a2094a-fab6-4e81-ac4f-2b3184a9d47e"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-04-19"}],"displaytype":"detail","filename":"kou_799.pdf","filesize":[{"value":"197.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"論文内容要旨・審査結果要旨","url":"https://osaka-dent.repo.nii.ac.jp/record/157/files/kou_799.pdf"},"version_id":"dc50210c-fb26-4dc7-bf36-36c62da70690"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Xerostomia|Spray-type oral moisturizer|γ-PGA|Dry mouth|Stress marker","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Evaluation of environmental change in the mouth with the use of spray-type oral moisturizer containing γ-PGA","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Evaluation of environmental change in the mouth with the use of spray-type oral moisturizer containing γ-PGA"}]},"item_type_id":"10006","owner":"16","path":["17"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-04-19"},"publish_date":"2017-04-19","publish_status":"0","recid":"157","relation_version_is_last":true,"title":["Evaluation of environmental change in the mouth with the use of spray-type oral moisturizer containing γ-PGA"],"weko_creator_id":"16","weko_shared_id":-1},"updated":"2023-05-15T14:17:56.564302+00:00"}