{"created":"2023-05-15T13:57:29.445774+00:00","id":197,"links":{},"metadata":{"_buckets":{"deposit":"2eb3d657-725b-4266-9c33-4e27f1d741f3"},"_deposit":{"created_by":16,"id":"197","owners":[16],"pid":{"revision_id":0,"type":"depid","value":"197"},"status":"published"},"_oai":{"id":"oai:osaka-dent.repo.nii.ac.jp:00000197","sets":["1686642104765:1:33:23"]},"author_link":["579"],"item_10006_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"IL-12 ファミリーサイトカインの NK92 細胞に対する影響について"}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2018-03-29"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"大阪歯科大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"34408","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（歯学）"}]},"item_10006_description_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2017年度","subitem_description_type":"Other"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We investigated the effect of IL-12 family cytokines (IL-12, IL-23, IL-27 and IL-35) on NK92 cells. We confirmed that NK92 cells are classified as subpopulations of CD56bright CD16-. We measured the intracellular granules and cytokines by flow cytometry. We could not observe the effect of IL-12 family cytokines (IL-23, IL-27 and IL-35) other than IL-12 in perforin 1 and IFN-γ production. A small amount of granzyme B production was detected by stimulation of IL-12, IL-27 or IL-35. These results suggested the possibility that IL-27 or IL-35 has an effect on granzyme B production of NK92 cells. ","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"乙第1610号"}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大島, 隆志"},{"creatorName":"オオシマ, タカシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"579","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-07-05"}],"displaytype":"detail","filename":"otu_1610.txt.pdf","filesize":[{"value":"348.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"学位論文","url":"https://osaka-dent.repo.nii.ac.jp/record/197/files/otu_1610.txt.pdf"},"version_id":"58550fdc-1c80-4ca0-846e-4fb2bd4b7b66"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-05-18"}],"displaytype":"detail","filename":"otu_1610.pdf","filesize":[{"value":"181.7 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"論文内容要旨・審査結果要旨","url":"https://osaka-dent.repo.nii.ac.jp/record/197/files/otu_1610.pdf"},"version_id":"db305383-4079-4bfa-8b2b-1fccdc629b24"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Interleukin-12 family cytokines｜NK cells","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Effect of IL-12 family cytokines on NK92 cells","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effect of IL-12 family cytokines on NK92 cells"}]},"item_type_id":"10006","owner":"16","path":["23"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-05-18"},"publish_date":"2018-05-18","publish_status":"0","recid":"197","relation_version_is_last":true,"title":["Effect of IL-12 family cytokines on NK92 cells"],"weko_creator_id":"16","weko_shared_id":-1},"updated":"2023-05-15T14:20:00.159440+00:00"}