{"created":"2023-05-15T13:57:31.138722+00:00","id":224,"links":{},"metadata":{"_buckets":{"deposit":"c1dc2fee-5548-4b15-92f1-6a4c0061f212"},"_deposit":{"created_by":16,"id":"224","owners":[16],"pid":{"revision_id":0,"type":"depid","value":"224"},"status":"published"},"_oai":{"id":"oai:osaka-dent.repo.nii.ac.jp:00000224","sets":["1686642104765:1:35:39"]},"author_link":["621","620"],"item_10006_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"ナノ構造析出純チタンへのアメロジェニンのコーティングが生体適合性に与える効果"}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2019-03-08"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"大阪歯科大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"34408","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（歯学）"}]},"item_10006_description_10":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2018年度","subitem_description_type":"Other"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The interactions between implants and host tissues depend on several factors. In particular, a growing body of evidence has demonstrated that the surface texture of an implant influences the response of the surrounding cells. The purpose of this study is to develop new implant materials aiming at the regeneration of periodontal tissues as well as hard tissues by coating nano-modified titanium with amelogenin, which is one of the main proteins contained in Emdogain. We confirmed by quartz crystal microbalance evaluation that amelogenin is easy to adsorb onto the nano-modified titanium surface as a coating. Scanning electron microscopy, scanning probe microscopy, X-ray photoelectron spectroscopy, and Fourier-transform infrared spectroscopy analyses confirmed that amelogenin coated the nano-modified titanium surface following alkali-treatment. In vitro evaluation using rat bone marrow and periodontal ligament cells revealed that the initial adhesion of both cell types and the induction of hard tissue differentiation such as cementum were improved by amelogenin coating. Additionally, the formation of new bone in implanted surrounding tissues was observed in in vivo evaluation using rat femurs. Together, these results suggest that this material may serve as a new implant material with the potential to play a major role in the advancement of clinical dentistry.","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第853号"}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"寺田, 知里"},{"creatorName":"テラダ, チサト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"620","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Terada, Chisato","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"621","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-16"}],"displaytype":"detail","filename":"kou_853_txt.pdf","filesize":[{"value":"1.8 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"学位論文","url":"https://osaka-dent.repo.nii.ac.jp/record/224/files/kou_853_txt.pdf"},"version_id":"13176671-4a9b-414b-a192-83589d19e81b"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-05-17"}],"displaytype":"detail","filename":"kou_853.pdf","filesize":[{"value":"199.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"論文内容要旨・審査結果要旨","url":"https://osaka-dent.repo.nii.ac.jp/record/224/files/kou_853.pdf"},"version_id":"04c0b59b-37df-448b-8c51-dbcf2ff86535"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"amelogenin｜host-implant interaction｜nanostructure｜tissue regeneration","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Effect of Amelogenin Coating of a Nano-Modified Titanium Surface on Bioactivty","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effect of Amelogenin Coating of a Nano-Modified Titanium Surface on Bioactivty"}]},"item_type_id":"10006","owner":"16","path":["39"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-05-17"},"publish_date":"2019-05-17","publish_status":"0","recid":"224","relation_version_is_last":true,"title":["Effect of Amelogenin Coating of a Nano-Modified Titanium Surface on Bioactivty"],"weko_creator_id":"16","weko_shared_id":-1},"updated":"2023-05-15T14:29:56.633501+00:00"}