{"created":"2023-05-15T13:57:31.410233+00:00","id":230,"links":{},"metadata":{"_buckets":{"deposit":"9530b420-8f8a-448d-be46-52086d7fb4d9"},"_deposit":{"created_by":18,"id":"230","owner":"16","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"230"},"status":"published"},"_oai":{"id":"oai:osaka-dent.repo.nii.ac.jp:00000230","sets":["1686642104765:1:40:41"]},"author_link":["633"],"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2019-06-25"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"大阪歯科大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"Osaka Dental University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"34408","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（歯学）","subitem_degreename_language":"ja"}]},"item_10006_description_7":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Antimicrobial photodynamic therapy has been used in clinics to minimize the susceptibility to bacterial resistance in patients with periodontal disease. It has been proven to be effective in treating bacterial, fungal, and viral infections. However, it is hard to ignore the effects of photosensitizers on the body. We investigated the effects of two typical photosensitizers, and assessed the proliferation of human gingival epithelial cells (HGECs) and the production of inflammatory cytokines after treatment with a high-power, red light-emitting diode (LED) along with photosensitizers. We found that methylene blue promotes proliferation of HGECs, whereas toluidine blue does not. The production of the inflammatory cytokines from HGECs decreases after LED irradiation. Hence, this study suggests that LED irradiation in the presence of either of the photosensitizers reduces inflammation in dental tissues such as the epithelium of periodontal pockets.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"乙第1620号"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中島, 幸市朗","creatorNameLang":"ja"},{"creatorName":"ナカジマ, コウイチロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Nakajima, Koichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"633","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-09-27"}],"filename":"otu_1620.pdf","filesize":[{"value":"199.0 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"論文内容要旨・審査結果要旨","objectType":"abstract","url":"https://osaka-dent.repo.nii.ac.jp/record/230/files/otu_1620.pdf"},"version_id":"2ef44646-0bb9-400f-bcb6-2a0e3100c28a"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-01-29"}],"filename":"otu_1620.txt.pdf","filesize":[{"value":"282.0 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"学位論文","objectType":"fulltext","url":"https://osaka-dent.repo.nii.ac.jp/record/230/files/otu_1620.txt.pdf"},"version_id":"ee1da42f-9ae5-423b-bcac-e1e6c0e3401e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Antimicrobial","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Photodynamic therapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Photosensitizer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Epithelial cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Effects of photosensitizers in a high-power, red light-emitting diode irradiation on human gingival epithelial cells","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of photosensitizers in a high-power, red light-emitting diode irradiation on human gingival epithelial cells","subitem_title_language":"en"},{"subitem_title":"高出力赤色LED照射における光増感剤がヒト歯肉上皮細胞に及ぼす影響","subitem_title_language":"ja"}]},"item_type_id":"10006","owner":"18","path":["41"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-09-27"},"publish_date":"2019-09-27","publish_status":"0","recid":"230","relation_version_is_last":true,"title":["Effects of photosensitizers in a high-power, red light-emitting diode irradiation on human gingival epithelial cells"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2025-01-21T06:37:39.150624+00:00"}