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Effect of β-tricalcium phosphate and porous hydroxyapatite bone substitutes on bone regeneration in alveolar bone defects around dental implants
https://osaka-dent.repo.nii.ac.jp/records/20
https://osaka-dent.repo.nii.ac.jp/records/2018b95d93-db93-4be1-b7a7-696485869673
| 名前 / ファイル | ライセンス | アクション |
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学位論文 (2.4 MB)
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論文内容要旨・審査結果要旨 (221.0 kB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||||
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| 公開日 | 2016-08-01 | |||||||||||
| 本文言語 | ||||||||||||
| 言語 | eng | |||||||||||
| タイトル | ||||||||||||
| タイトル | Effect of β-tricalcium phosphate and porous hydroxyapatite bone substitutes on bone regeneration in alveolar bone defects around dental implants | |||||||||||
| 著者 |
井奥, 雄介
× 井奥, 雄介
× Ioku, Yusuke
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| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Implant | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Autologous bone | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | β-TCP | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | HA | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Implant | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Autologous bone | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | β-TCP | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | HA | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||||
| 資源タイプ | doctoral thesis | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Although artificial materials are preferred over biological bone substitutes because there is no risk of infection, clinical outcomes are less favorable. We histologically investigated the influence on new bone formation of two types of artificial bone substitutes used to fill in experimental bone defects around implants. Nine dogs were used as the experimental animals, the bilateral mandibular, premolars were extracted, and, after a 3-month observation of osseous healing, 4 bone defects with a diameter of 5.0 mm and a depth of 10 mm were prepared in the alveolar bone of the extracted regions in each animal using a trephine bur. Implants were placed in the distal regions of the bone defects, and the animals were divided into 4 groups : Bone defects around the implants were filled with porous hydroxyapatite (HA), autologous bone, β-tricalcium phosphate (β-TCP), or not filled (controls). The wounds were completely closed, and samples were collected 2, 4 and 8 weeks after the implant treatment. Bone mass continuously increased in the β-TCP group, whereas no increase was noted over 8 weeks in the HA group. No significant difference was observed between the β-TCP and control groups. New bone formation was observed earlier in the β-TCP group than in the HA group. Since HA is not absorbed by osteoclasts, the entrance of cells, such as osteoblasts, into the filled material may have been delayed in the HA group, resulting in the delayed formation of new bone, for which a combination with inclusion of autologous bone may be desirable. | |||||||||||
| 学位名 | ||||||||||||
| 学位名 | 博士（歯学） | |||||||||||
| 学位授与機関 | ||||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||||
| 学位授与機関識別子 | 34408 | |||||||||||
| 学位授与機関名 | 大阪歯科大学 | |||||||||||
| 学位授与年月日 | ||||||||||||
| 学位授与年月日 | 2015-03-06 | |||||||||||
| 学位授与番号 | ||||||||||||
| 学位授与番号 | 甲第758号 | |||||||||||
