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レセプトデータを用いた口腔・咽頭がん患者に対するセツキシマブの治療実態に関する疫学研究
https://osaka-dent.repo.nii.ac.jp/records/2000100
https://osaka-dent.repo.nii.ac.jp/records/2000100c9395e58-f3ef-454a-ab00-760309023d68
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
本文内容要旨・審査結果要旨 (279 KB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||||
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| 公開日 | 2024-06-01 | |||||||||||
| 本文言語 | ||||||||||||
| 言語 | eng | |||||||||||
| タイトル | ||||||||||||
| タイトル | Cost analysis among oral cancer patients with and without cetuximab using administrative claims database in Japan | |||||||||||
| 言語 | en | |||||||||||
| タイトル | ||||||||||||
| タイトル | レセプトデータを用いた口腔・咽頭がん患者に対するセツキシマブの治療実態に関する疫学研究 | |||||||||||
| 言語 | ja | |||||||||||
| 著者 |
北山, 貴也
× 北山, 貴也
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| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Oral cancer | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Cetuximab | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Administrative | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | claims database | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||||
| 資源タイプ | doctoral thesis | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | metadata only access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||||
| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | This study aimed to examine the medical costs associated with oral and pharyngeal cancers using a large administrative claims database in Japan. Economic evaluation is crucial for maintaining universal health coverage in Japan. This study used the administrative claims database of 21,736 patients diagnosed with oral or pharyngeal cancer between April 2005 and December 2020. We calculated propensity scores based on age, sex, cancer site, lymph node metastasis, and first treatment. Using propensity score matching, we selected 195 participants from each group and compared treatment cost with and without cetuximab. The average monthly medical cost was 525,551 and 285,239 yen for the cetuximab administration and non-administration groups, respectively. When compared by sex, age, and cancer site, costs remained significantly higher for oral and pharyngeal than for salivary gland cancers. Among the conditions during treatment, 11.8% of patients experienced hypomagnesemia due to cetuximab administration, while 7.7% exhibited common acne. Patients in the cetuximab administration group were more commonly diagnosed with cancer-related pain, oral mucositis, and difficulties with oral intake. The cost for patients with oral cancer is related to patient characteristics and treatment patterns. Acknowledging the high medical expenses and need for careful attention to complications that may occur is essential. | |||||||||||
| 言語 | en | |||||||||||
| 学位名 | ||||||||||||
| 言語 | ja | |||||||||||
| 学位名 | 博士（歯学） | |||||||||||
| 学位授与機関 | ||||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||||
| 学位授与機関識別子 | 34408 | |||||||||||
| 言語 | ja | |||||||||||
| 学位授与機関名 | 大阪歯科大学 | |||||||||||
| 言語 | en | |||||||||||
| 学位授与機関名 | Osaka Dental University | |||||||||||
| 学位授与年月日 | ||||||||||||
| 学位授与年月日 | 2024-03-01 | |||||||||||
| 学位授与番号 | ||||||||||||
| 学位授与番号 | 甲第988号 | |||||||||||
