| Item type |
学位論文 / Thesis or Dissertation(1) |
| 公開日 |
2021-04-23 |
| 本文言語 |
|
|
言語 |
eng |
| タイトル |
|
|
タイトル |
Elucidation of the Mechanism of Bone Regeneration When a Mixture of β-TCP and Autologous Bone Granules are Transplanted |
| 著者 |
辰村, 正泰
Tatsumura, Masayasu
|
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
autologous bone graft |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
β-TCP granules |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
micro-CT |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
picrosirius red staining |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
col-lagen |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
vWF immunostaining |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_db06 |
|
資源タイプ |
doctoral thesis |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We examined the amount and maturity of collagen as a parameter for bone quality in the graft material transplanted into a rat skull bone defect model. Male SD rats were used to generate an experimental animal model of skull defects. The obtained autologous bone granules and β-TCP granules were mixed at a ratio of 1:1 to prepare a graft material that combines autologous bone with β-TCP granules. At 8 weeks after transplantation, the β-TCP+ autologous bone and the autologous bone groups showed BV/TV values, measured based on CT image analysis, significantly different from those in the β-TCP and control groups. The β-TCP+ autologous bone group exhibited the ability to form blood vessels into the graft material for a longer period of time after transplantation compared to that in the autologous bone group, as well as the elevated production of collagen into β-TCP granules during the bone formation process compared to that in the β-TCP group. |
| 学位名 |
|
|
学位名 |
博士（歯学） |
| 学位授与機関 |
|
|
|
学位授与機関識別子Scheme |
kakenhi |
|
|
学位授与機関識別子 |
34408 |
|
|
学位授与機関名 |
大阪歯科大学 |
| 学位授与年月日 |
|
|
学位授与年月日 |
2021-03-05 |
| 学位授与番号 |
|
|
学位授与番号 |
甲第908号 |
学位論文 (1.9 MB)
