Item type |
学位論文 / Thesis or Dissertation(1) |
公開日 |
2022-05-13 |
本文言語 |
|
|
言語 |
eng |
タイトル |
|
|
タイトル |
Cell viability of fine powders in hybrid resins and ceramic materials for CAD/CAM |
著者 |
中井, 真理子
Nakai, Mariko
|
キーワード |
|
|
主題Scheme |
Other |
|
主題 |
CAD/CAM|Composite resin blocks|Ceramic blocks|Cell viability |
資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_db06 |
|
資源タイプ |
doctoral thesis |
アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Resin blocks and ceramic blocks for CAD/CAM crowns were cut into powders and separated into three particle size groups. Oxidative stress and cell viability were measured in 3T3 and FRSK cells. The results of cytotoxicity tended to be slightly higher for resin than for ceramics. The values also increased as the particle size decreased in the powders. In addition, incorporation into cells was frequently observed under SEM, suggesting that the particle size of easily incorporated dust is different among cell types. FACS showed an increase in apoptosis and a decrease in cell viability in most of the sample groups compared to the control group. Hematoxylin and eosin staining of the cells showed deep staining of the nuclei in the sample groups. It was found that oxidative stress cell viability and apoptosis appeared differently depending on the size of the particles and the type of cells. |
学位名 |
|
|
学位名 |
博士(歯学) |
学位授与機関 |
|
|
|
学位授与機関識別子Scheme |
kakenhi |
|
|
学位授与機関識別子 |
34408 |
|
|
学位授与機関名 |
大阪歯科大学 |
学位授与年月日 |
|
|
学位授与年月日 |
2022-03-04 |
学位授与番号 |
|
|
学位授与番号 |
甲第928号 |